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Cambridge Centre for Frontotemporal Dementia and Related Disorders

Department of Clinical Neurosciences
 

I am interested in the study of neuropathology, biomarkers and clinical features of neurodegenerative diseases, with special interest in frontotemporal lobar degeneration (FTLD) and Alzheimer's disease (AD).

My work focuses on the application of neuroimaging techniques (multi-tracer PET and MRI) to investigate the pathophysiology of neurodegenerative diseases, in order to identify early diagnostic and prognostic markers.

To this end, I apply longitudinal statistical models and multimodal imaging analyses, with an interdisciplinary approach that integrates imaging and clinical data with fluid markers and post-mortem pathology.

My main projects focus on:

i) characterising the predictive value of in vivo PET imaging for molecular pathology and inflammation in tauopathies;

ii) identifying novel clinically viable PET and fluid biomarkers in dementias;

iii) investigating the role of behavioural and brain changes in pre-symptomatic genetic frontotemporal dementia.

Research

I am interested in the study of neuropathology, biomarkers and clinical features of neurodegenerative diseases. My work focuses on the application of neuroimaging techniques, such as PET and MRI, to describe progressive brain changes in dementia and related disorders, in order to identify early diagnostic and prognostic markers.

Post-doctoral Fellow
E-mail: mm2243[at]cam.ac.uk
 Maura  Malpetti

Contact Details

Cambridge Centre for
Frontotemporal Dementia and related disorders
Department of Clinical Neurosciences
University of Cambridge
Herchel Smith Building, Forvie Site
Robinson Way, Cambridge Biomedical Campus
Cambridge
CB2 0SZ
Not available for consultancy

Affiliations

Classifications: 

Title: "Frontotemporal dementia: introduction and pathways to progress"

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A new short film by Professor Rowe about his journey as a clinician and researcher. Sponsored by AlzheimersResearchUK.

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