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Cambridge Centre for Frontotemporal Dementia and Related Disorders

Department of Clinical Neurosciences

Studying at Cambridge


Topic 6 - Computational Neurosciences

Computational Neuroscience - from Neuron to Behaviour

We also use computational neurosciences approaches such as mathematical modelling and machine learning in order to understand behaviour such as decision making, impulsivity, and action inhibition. We investigate those mechanisms in healthy populations, healthy elderly participants as well as patients with either dementia or parkinsonisms. 




Selected Publications

  • Zhang, J., Rittman, T., Nombela, C., Fois, A., Coyle-Gilchrist, I., Barker, R. A., Hughes, L. E., & Rowe, J. B. (2016). Different decision deficits impair response inhibition in progressive supranuclear palsy and Parkinson's disease. Brain, 139(Pt 1), 161-173. doi:10.1093/brain/awv331 PMID: 26582559 PMC4949391
  • Zhang, J., Nombela, C., Wolpe, N., Barker, R. A., & Rowe, J. B. (2016). Time on timing: Dissociating premature responding from interval sensitivity in Parkinson's disease. Mov Disord, 31(8), 1163-1172. doi:10.1002/mds.26631 PMID: 27091513 PMC4988382

Hannah Diver created this moving short film about dementia and its impact as a 6th form project

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Interview about new article with Thomas Cope on ITV Anglia

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Emily Fisher, a postgraduate student from the Norwich University of the Arts, created an animated film about a person's experience suffering from Alzheimer's disease.

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Video abstract for the new article by Lansdall et al., (2017) published in Brain.

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